Ethanesulfonic acid, 2-[[(3α,5β,6α,7α)-6-ethyl-3,7-dihydroxy-24-oxocholan-24-yl]amino]-

Name	Tauro Obeticholic acid
Synonyms	Tauro Obeticholic acid Obeticholic Acid Impurity 56 Tauro-Obeticholic AcidDISCONTINUED. Please see T009025. Ethanesulfonic acid, 2-[[(3α,5β,6α,7α)-6-ethyl-3,7-dihydroxy-24-oxocholan-24-yl]amino]-
CAS	863239-61-6

Molecular Formula	C28H49NO6S
Molar Mass	527.76
Density	1.177±0.06 g/cm3(Predicted)
pKa	1.42±0.50(Predicted)
Storage Condition	-20°C
In vitro study	Obeticholic acid is conjugated with taurine in the liver to form Tauro-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate Tauro-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces.

biological activity

Tauro-Obeticholic acid is an active metabolite of taurine. Objective Acid is an orally bioavailable farnesoid X receptor (FXR) agonist.

Last Update：2024-04-09 21:54:55

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Ethanesulfonic acid, 2-[[(3α,5β,6α,7α)-6-ethyl-3,7-dihydroxy-24-oxocholan-24-yl]amino]- Request for Quotation